Chloroplast protein targeting and organelle biogenesis
B215 Birge Hall
430 Lincoln Dr
Madison, WI 53706
Plant Biology; Membrane Biology & Protein Trafficking
We are interested in the molecular and cellular basis of developmental transitions in plants. In past projects, we investigated the role of MADS domain factors in regulation of flowering time, floral organ abscission, and pollen growth and development. In current projects, we are investigating protein sorting during plastid biogenesis. Plastids are transformed from relatively undifferentiated proplastids into a variety of differentiated forms (chloroplasts, chromoplasts, amyloplasts, etc.) through changes in protein composition and membrane organization. This is mediated by targeting and translocation systems that ensure the proteins are directed to the right place at the right time. We are using a combination of genetics, molecular biology, and biochemistry to study the roles of the inner envelope SEC2 protein translocase system and stromal targeting factors in plastid biogenesis.