Randall Kimple

Credentials: Human Oncology Department

Position title: HPV associated cancers; therapeutic resistance in cancer

Email: rkimple@humonc.wisc.edu

Phone: (608) 263-3611

Address:
3107 Wi Institute Medical Research
1111 Highland Ave
Madison, WI 53705

Headshot

lab website:

https://www.humonc.wisc.edu/team_member/randall-kimple/#research

focus groups:

Cancer Biology; Virology

research description:

We utilize cellular systems that include cell lines and unique early passage cell strains of both HPV-positive and HPV-negative head and neck cancer. We use these cellular systems to investigate how the HPV-oncoproteins work to modulate the response to radiation and/or chemotherapy. In particular, we focus our efforts on modulation of cellular signaling pathways such as EGFR, MEK/ERK/PI3K/Akt by the HPV proteins E5 and E6 and on DNA damage repair by the HPV protein E7.

ALSO A TRAINER IN THE FOLLOWING PROGRAMS: Cellular and Molecular Pathology (CMP), Cancer Biology, Comparative Biomedical Sciences (CBMS)

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