Freya Mowat

Credentials: Ophthalmology and Visual Sciences Department

Position title: Retinal photoreceptor metabolism and aging

Email: mowat@wisc.edu

Phone: 608-264-2668

Address:
687Medical Sciences
1300 University Avenue
Madison WI 53706

Headshot of Freya Mowat

lab website:

https://mowat.ophth.wisc.edu/

focus groups:

Cellular & Molecular Metabolism; Transcriptional Mechanisms

research description:

The main focus in our new lab is to advance understanding of age-related changes in outer retinal metabolism and to define mechanisms of age-related outer retinal functional impairment and neuron loss. These mechanisms are relevant to the pathophysiology of human age-related macular degeneration (AMD) and our ultimate goal is to characterize pathways amenable to therapeutic intervention for AMD. We use multiple molecular techniques and tissue pathology to define pathways relevant to healthy (and unhealthy) retinal metabolism and aging. Our current focus is to define the importance of the transcriptional regulator, PGC-1alpha on mitochondrial structure and function in the aging retina.

ALSO A TRAINER IN THE FOLLOWING PROGRAMS: Comparative Biomedical Sciences (CBMS) 

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