Credentials: Ophthalmology and Visual Sciences Department
Position title: Retinal photoreceptor metabolism and aging
1300 University Avenue
Madison WI 53706
Cellular & Molecular Metabolism; Transcriptional Mechanisms
The main focus in our new lab is to advance understanding of age-related changes in outer retinal metabolism and to define mechanisms of age-related outer retinal functional impairment and neuron loss. These mechanisms are relevant to the pathophysiology of human age-related macular degeneration (AMD) and our ultimate goal is to characterize pathways amenable to therapeutic intervention for AMD. We use multiple molecular techniques and tissue pathology to define pathways relevant to healthy (and unhealthy) retinal metabolism and aging. Our current focus is to define the importance of the transcriptional regulator, PGC-1alpha on mitochondrial structure and function in the aging retina.
ALSO A TRAINER IN THE FOLLOWING PROGRAMS: Comparative Biomedical Sciences (CBMS)