Cell & Regenerative Biology Department
Human ES cells and the biology of pluripotency
Morgridge Inst Research
330 N Orchard St
Madison, WI 53715
Developmental Biology & Regenerative Medicine
We are studying the developmental potential of human ES cells in lineage-specific differentiation (such as blood, trophoblast, neural tissue, and heart) in collaborative efforts with UW physician-scientists. My research focuses on understanding how a cell can maintain or change identity, how a cell chooses between self-renewal and the initial decision to differentiate, and how a differentiated cell with limited developmental potential can be reprogrammed to a pluripotent cell.