Credentials: Biochemistry Department
Position title: RNA and gene control; role of RNA regulation in development and the nervous system
Phone: (608) 262-8007
433 Babcock Dr
Madison, WI 53706
RNA Biology; Systems Biology
We are interested in how RNAs are controlled in eukaryotic cells. We want to understand the mechanisms that underlie control of their translation, decay, and movements. In parallel, we concentrate on their biological roles and the evolution of RNA regulatory networks. To do so, we concentrate on families of regulatory proteins that activate and repress batteries of mRNAs. We exploit a range of organisms, including yeast, worms and frog oocytes, with a special interest in regulation during development. Our approaches combine molecular genetics, biochemistry, structural biology and genomics.