University of Wisconsin–Madison
Photo of Golgi outposts illuminated in the dendrites of a sensory neuron illustrate the polarized distribution of the secretory system in neurons

Golgi outposts illuminated in the dendrites of a sensory neuron illustrate the polarized distribution of the secretory system in neurons. (Mike Kelliher)

Cell Adhesion and Cytoskeleton

The cell is the fundamental unit of life, making it essential to understand how cells divide, function, and signal. Disruption of these primary cellular processes has been associated with tumor development as well as aberrant cell and tissue function in human disease. Cell Adhesion & Cytoskeleton focus group members investigate topics ranging from cell division to cytoskeletons to signaling to migration. Our members leverage a variety of cutting-edge cross-disciplinary approaches that combine cell biology with innovative biochemistry, genetics, molecular biology, and microscopy techniques. The integration of these sophisticated approaches enables multiscale insight into how cells work. In their research, members use cells in culture and model organisms, including zebrafish, mice, and fruit flies. Madison has a rich tradition of collaborative research. Reflecting this, there are several campus-wide group meetings that bring together Cell Adhesion & Cytoskeleton members and other researchers interested in cell biology. These include the weekly Cell Biology Study Group (CBSG) and the Cell Division meeting.

Headshot

Focus Group Chair Jill Wildonger
Biochemistry Department
Microtubule-based transport in developing neurons
wildonger@wisc.edu

Focus Group Members

Richard Anderson

Medical School Dean's Office

Molecular and cellular signaling and cancer

raanders@wisc.edu

William Bement

Laboratory of Cell and Molecular Biology & Integrative Biology Department

Signal transduction, cell division, and cytoskeleton

wmbement@facstaff.wisc.edu

Seth Blair

Integrative Biology Department

Development and signaling in Drosophila

ssblair@facstaff.wisc.edu

Mark Burkard

Medicine Department

Mitotic kinase function and cancer

mburkard@wisc.edu

Michael Cahill

Comparative Biosciences Department

Molecular and biochemical mechanisms of synapse morphogenesis

michael.cahill@wisc.edu

Erik Dent

Neuroscience Department

Regulation of the cytoskeleton in neuronal differentiation

ewdent@wisc.edu

Timothy Gomez

Neuroscience Department

Regulation of axon guidance

tmgomez@facstaff.wisc.edu

Jeffrey Hardin

Integrative Biology Department

Morphogenesis and pattern formation during early development

jdhardin@wisc.edu

Troy Hornberger

Comparative Biosciences Department

Mechanotransduction and the regulation of skeletal muscle mass

troy.hornberger@wisc.edu

Anna Huttenlocher

Pediatrics Department

Cellular and molecular mechanisms that regulate cell migration and chemotaxis in cancer and inflammation

huttenlocher@wisc.edu

Patrick Masson

Genetics Department

Molecular genetics of root growth behavior in response to mechanical stimuli

phmasson@wisc.edu

Deane Mosher

Biomolecular Chemistry Department

Biochemistry of cell adhesion and the extracellular matrix

dfm1@medicine.wisc.edu

Sara Patterson

Horticulture Department

Regulation of cell separation and adhesion in Arabidopsis

spatters@wisc.edu

Francisco Pelegri

Genetics Department

Genetic control of zebrafish embryogenesis

fjpelegri@wisc.edu

Donna Peters

Pathology & Laboratory Medicine Department

Role of extracellular matrix and integrin signaling in human eye

dmpeter2@wisc.edu

Alan Rapraeger

Human Oncology Department

Regulation of tumor proliferation, invasion and survival by adhesion receptor signaling mechanisms

rapraeger@humonc.wisc.edu

Nader Sheibani

Opthalmology & Visual Sciences Department

Cell adhesion and signaling in vascular cells

nsheibanikar@wisc.edu

Beth Weaver

Cell & Regenerative Biology Department

Mitosis, chromosome segregation, aneuploidy and cancer

baweaver@wisc.edu