In recent years, there has been a resurgence of interest in metabolism and an appreciation for its central role in wide range of cellular and molecular process. Metabolic disorders including obesity, diabetes, hypertension and atherosclerotic heart disease are among the most prominent and costly conditions affecting people worldwide. It is becoming clear that these and other common diseases such as cancer and neurodegenerative disorders, result from alterations in both classic and newly defined metabolic pathways. Researches in the Cellular and Molecular Metabolism focus group are leveraging a wide array of techniques, ranging from mass spectrometry-based proteomics and metabolomics to organismal physiology and genetics, to explore these problems and their molecular underpinnings.
Focus Group Chair Dudley Lamming
Medicine Department
Regulation of metabolism by nutrient signaling pathways
lamming@wisc.edu
Focus Group Members
Caroline Alexander
Credentials: Oncology Department
Position title: Skin and metabolic physiology
Email:
alexander
Rozalyn Anderson
Credentials: Medicine Department
Position title: Metabolism of aging and age-related disease
Email:
rozalyn.anderson
Alan Attie
Credentials: Biochemistry Department
Position title: Molecular genetics of diabetes & insulin resistance; cell biology of lipoprotein assembly, cholesterol trafficking
Email:
adattie
Barak Blum
Credentials: Cell & Regenerative Biology Department
Position title: Functional beta cell maturation
Email:
bblum4
Jacob Brunkard
Credentials: Genetics Department
Position title: Molecular mechanisms regulating plant metabolism
Email:
brunkard
Jason Cantor
Credentials: Biochemistry Department
Position title: Influence of environmental factors on human cell metabolism
Email:
jcantor
Vincent Cryns
Credentials: Medicine Department
Position title: Mechanisms of cell death in disease
Email:
vlcryns
Dawn Davis
Credentials: Medicine, Division of Endocrinology
Position title: Pancreatic islet biology
Email:
dbd
John Denu
Credentials: Biomolecular Chemistry Department
Position title: Mechanisms of chromatin dynamics, epigenetics, metabolism, and signaling
Email:
jmdenu
Timothy Donohue
Credentials: Bacteriology Department
Position title: Process & control of bioenergy generation
Email:
tdonohue
Richard Eisenstein
Credentials: Nutritional Sciences Department
Position title: Molecular control of vertebrate iron metabolism
Email:
eisenste
Feyza Engin
Credentials: Biomolecular Chemistry Department
Position title: Endoplasmic reticulum stress, organelle dysfunction, unfolded protein response, beta cell function and diabetes
Email:
fengin
Jing Fan
Credentials: Nutritional Sciences Department
Position title: Mammalian cellular metabolism; metabolic regulation; tumor microenvironment
Email:
jfan4
Andrea Galmozzi
Credentials: Medicine Department
Position title: Intracellular trafficking of signaling metabolites
Email:
agalmozzi
Wei Guo
Credentials: Animal Health & Biomedical Sciences
Position title: Muscle Structure and Function, RNA Biology
Email:
wguo2
Troy Hornberger
Credentials: Comparative Biosciences Department
Position title: Mechanotransduction and the regulation of skeletal muscle mass
Email:
troy.hornberger
Andrew Hryckowian
Credentials: Medicine and Medical Microbiology & Immunology Department
Position title: Molecular mechanisms of microbiome dynamics
Email:
Hryckowian
Tu-Anh Huynh
Credentials: Food Science Department
Position title: C-di-AMP signaling in bacterial physiology and pathogenesis
Email:
thuynh6
Nancy Keller
Credentials: Medical Microbiology & Immunology Department
Position title: Aspergillus cell biology
Email:
npkeller
Patricia Kiley
Credentials: Biomolecular Chemistry Department
Position title: Molecular genetics and biochemistry of oxygen regulated gene expression and transcription activation
Email:
pjkiley
Michelle Kimple
Credentials: Medicine Department
Position title: Regulation of pancreatic beta-cell biology
Email:
mkimple
Adam Konopka
Credentials: Medicine Department
Position title: Musculoskeletal aging and metabolism
Email:
akonopka
Hiroshi Maeda
Credentials: Botany Department
Position title: Amino acid homeostasis in plants
Email:
maeda2
Ahmed Mahmoud
Credentials: Cell & Regenerative Biology Department
Position title: Mammalian Heart Regeneration
Email:
aimahmoud
Mark Mandel
Credentials: Medical Microbiology & Immunology Department
Position title: Genetic analysis of bacterial colonization
Email:
mmandel
Thomas Martin
Credentials: Biochemistry Department
Position title: Mechanisms of hormone action; regulation of hormone/neurotransmitter secretion
Email:
tfmartin
Matthew Merrins
Credentials: Medicine
Position title: Beta cell biology and diabetes
Email:
merrins
Freya Mowat
Credentials: Ophthalmology and Visual Sciences Department
Position title: Retinal photoreceptor metabolism and aging
Email:
mowat
Jon Odorico
Credentials: Surgery Department
Position title: Embryonic stem cells to generate insulin producing cells for the treatment of diabetes and to study pancreatic islet development
Email:
jon
Brian Parks
Credentials: Nutritional Sciences Department
Position title: Causal genes of metabolic diseases
Email:
brian.w.parks
Luigi Puglielli
Credentials: Medicine Department
Position title: Molecular mechanisms of neurodevelopment and neurodegeneration
Email:
lp1
Claire Richardson
Credentials: Genetics
Position title: Cellular & molecular neurobiology, aging
Email:
Claire.richardson
Avtar Roopra
Credentials: Neuroscience Department
Position title: Regulation of chromatin structure in neurons and cancer
Email:
asroopra
Nader Sheibani
Credentials: Ophthalmology & Visual Sciences Department
Position title: Cell adhesion and signaling in vascular cells
Email:
nsheibanikar
Judith Simcox
Credentials: Biochemistry Department
Position title: Lipid metabolism in cold exposure
Email:
jsimcox
Melissa Skala
Credentials: Biomedical Engineering Department
Position title: Metabolism, cancer, microscopy
Email:
mcskala
John Svaren
Credentials: Comparative Biosciences Department
Position title: Transcriptional regulation of peripheral nerve myelination
Email:
jpsvaren
Randal Tibbetts
Credentials: Human Oncology Department
Position title: DNA repair; gene expression; neurodegeneration; amyotrophic lateral sclerosis
Email:
rstibbetts
Marcelo Vargas
Credentials: Neurology Department
Position title: Cell and molecular biology of astrocytes. Amyotrophic lateral sclerosis.
Email:
mvargas
Jade Wang
Credentials: Bacteriology Department
Position title: Stress and genome integrity in bacteria
Email:
wang
David Wassarman
Credentials: Medical Genetics Department
Position title: Neurodegeneration in Drosophila
Email:
dawassarman
Wei Xu
Credentials: Oncology Department
Position title: Epigenetic regulation of breast cancer
Email:
wxu