In recent years, there has been a resurgence of interest in metabolism and an appreciation for its central role in wide range of cellular and molecular process. Metabolic disorders including obesity, diabetes, hypertension and atherosclerotic heart disease are among the most prominent and costly conditions affecting people worldwide. It is becoming clear that these and other common diseases such as cancer and neurodegenerative disorders, result from alterations in both classic and newly defined metabolic pathways. Researches in the Cellular and Molecular Metabolism focus group are leveraging a wide array of techniques, ranging from mass spectrometry-based proteomics and metabolomics to organismal physiology and genetics, to explore these problems and their molecular underpinnings.
Focus Group Chair Dudley Lamming
Medicine Department
Regulation of metabolism by nutrient signaling pathways
lamming@wisc.edu
Focus Group Members
Caroline Alexander
Credentials: Oncology Department
Position title: Skin and metabolic physiology
Email:
alexander
Rozalyn Anderson
Credentials: Medicine Department
Position title: Metabolism of aging and age-related disease
Email:
rozalyn.anderson
Alan Attie
Credentials: Biochemistry Department
Position title: Molecular genetics of diabetes & insulin resistance; cell biology of lipoprotein assembly, cholesterol trafficking
Email:
adattie
Roméo Blanc
Credentials: Cell & Regenerative Biology
Position title: Epigenetic regulation of aging
Email:
rblanc
Barak Blum
Credentials: Cell & Regenerative Biology Department
Position title: Functional beta cell maturation
Email:
bblum4
Jacob Brunkard
Credentials: Genetics Department
Position title: Molecular mechanisms regulating plant metabolism
Email:
brunkard
Jason Cantor
Credentials: Biochemistry Department
Position title: Influence of environmental factors on human cell metabolism
Email:
jcantor
Josh Coon
Credentials: Biomolecular Chemistry
Position title: Systems and quantitative biology
Email:
jcoon
Vincent Cryns
Credentials: Medicine Department
Position title: Mechanisms of cell death in disease
Email:
vlcryns
Dawn Davis
Credentials: Medicine, Division of Endocrinology
Position title: Pancreatic islet biology
Email:
dbd
John Denu
Credentials: Biomolecular Chemistry Department
Position title: Mechanisms of chromatin dynamics, epigenetics, metabolism, and signaling
Email:
jmdenu
Timothy Donohue
Credentials: Bacteriology Department
Position title: Process & control of bioenergy generation
Email:
tdonohue
Daniela Drummond Barbosa
Credentials: Genetics
Position title: Physiology of stem cell lineages
Email:
ddbarbosa
Lee Eckhardt
Credentials: Medicine Department
Position title: Functional genomics approach to understand cardiac-arrhythmia
Email:
lle
Feyza Engin
Credentials: Biomolecular Chemistry Department
Position title: Endoplasmic reticulum stress, organelle dysfunction, unfolded protein response, beta cell function and diabetes
Email:
fengin
Jing Fan
Credentials: Medical Microbiology and Immunology Department
Position title: Mammalian cellular metabolism; metabolic regulation; tumor microenvironment
Email:
jfan4
Ting Fu
Credentials: Pharmacy Department
Position title: Nuclear receptor, Bile acids, Gut physiology, Colon cancer
Email:
ting.fu
Andrea Galmozzi
Credentials: Medicine Department
Position title: Intracellular trafficking of signaling metabolites
Email:
agalmozzi
Wei Guo
Credentials: Animal Health & Biomedical Sciences
Position title: Muscle Structure and Function, RNA Biology
Email:
wguo2
Troy Hornberger
Credentials: Comparative Biosciences Department
Position title: Mechanotransduction and the regulation of skeletal muscle mass
Email:
troy.hornberger
Andrew Hryckowian
Credentials: Medicine and Medical Microbiology & Immunology Department
Position title: Molecular mechanisms of microbiome dynamics
Email:
Hryckowian
Tu-Anh Huynh
Credentials: Food Science Department
Position title: C-di-AMP signaling in bacterial physiology and pathogenesis
Email:
thuynh6
Jiaoyang Jiang
Credentials: Pharmaceutical Sciences
Position title: Protein glycosylation in biology and disease
Email:
jiaoyang.jiang
Mehdi Kabbage
Credentials: Plant Pathology Department
Position title: Programmed Cell Death/Host-Microbe Interactions
Email:
kabbage
Nancy Keller
Credentials: Medical Microbiology & Immunology Department
Position title: Fungi, secondary metabolism, pathogenesis
Email:
npkeller
Michelle Kimple
Credentials: Medicine Department
Position title: GPCRs in pancreatic islet biology
Email:
mkimple
Adam Konopka
Credentials: Medicine Department
Position title: Musculoskeletal aging and metabolism
Email:
akonopka
Hiroshi Maeda
Credentials: Botany Department
Position title: Plant metabolic evolution and synthetic biology
Email:
maeda2
Mark Mandel
Credentials: Medical Microbiology & Immunology Department
Position title: Genetic analysis of bacterial colonization
Email:
mmandel
Sara McCoy
Credentials: Medicine Department
Position title: Mesenchymal stromal cell immunobiology
Email:
ssmccoy
Mark Meyer
Credentials: Nutritional Sciences Department
Position title: Investigating genomic mechanisms of transcription, metabolism, and disease progression
Email:
markmeyer
Jon Odorico
Credentials: Surgery Department
Position title: Pluripotent stem cell islets
Email:
jon
Marisa Otegui
Credentials: Botany Department & Center for Quantitative Cell Imaging
Position title: Cellular trafficking and signaling in plants
Email:
otegui
Brian Parks
Credentials: Nutritional Sciences Department
Position title: Causal genes of metabolic diseases
Email:
brian.w.parks
Bret Payseur
Credentials: Genetics
Position title: Evolution of extreme phenotypes
Email:
payseur
Luigi Puglielli
Credentials: Medicine Department
Position title: Metabolic crosstalk and proteostasis
Email:
lp1
Timothy Rhoads
Credentials: Nutritional Sciences Department
Position title: Gene expression regulation of metabolism and aging
Email:
timothy.rhoads
Claire Richardson
Credentials: Genetics
Position title: Cellular & molecular neurobiology, aging
Email:
Claire.richardson
Abbas Rizvi
Credentials: Neuroscience Department
Position title: Single cell and spatially resolved studies of gene regulation
Email:
ahrizvi
Nader Sheibani
Credentials: Ophthalmology & Visual Sciences Department
Position title: Cell adhesion and signaling in vascular cells
Email:
nsheibanikar
Judith Simcox
Credentials: Biochemistry Department
Position title: Lipid metabolism in cold exposure
Email:
jsimcox
Melissa Skala
Credentials: Biomedical Engineering Department
Position title: Metabolism, cancer, microscopy
Email:
mcskala
John Svaren
Credentials: Comparative Biosciences Department
Position title: Transcriptional regulation of peripheral nerve myelination
Email:
jpsvaren
Randal Tibbetts
Credentials: Human Oncology Department
Position title: DNA repair; gene expression; neurodegeneration; amyotrophic lateral sclerosis
Email:
rstibbetts
Marcelo Vargas
Credentials: Neurology Department
Position title: Cell and molecular biology of astrocytes. Amyotrophic lateral sclerosis.
Email:
mvargas
Jade Wang
Credentials: Bacteriology Department
Position title: Stress and genome integrity in bacteria
Email:
wang
David Wassarman
Credentials: Medical Genetics Department
Position title: Neurodegeneration in Drosophila
Email:
dawassarman
Jingshing Wu
Credentials: Pediatrics Department
Position title: Developmental Biology, Congenital Heart Disease, Genetics/Epigenetics
Email:
jwu7
Wei Xu
Credentials: Oncology Department
Position title: Epigenetic regulation of breast cancer
Email:
wxu