Lisa Arendt

Comparative Biosciences Department

Obesity, breast cancer, mouse models

(608) 890-2265

Veterinary Medicine Building
2015 Linden Dr
Madison, WI 53706


lab website:

focus groups:

Cancer Biology; Immunology

research description:

Obesity is becoming a global epidemic in both adults and children, leading to increased rates of multiple  types  of  cancer  including  breast,  kidney,  colorectal,  pancreatic,  and  esophageal.  Elucidating the role of adipose tissue biology in cancer is critical for prevention and treatment of obesity-­‐associated  cancer.    My  research  goal  is  to  examine  the  interactions  among  the  epithelia  and stromal cells that are deregulated under conditions of obesity leading to tumorigenesis, and our work is currently focused on breast cancer. We are interested in understanding how obesity alters cell signaling among stromal cells, including adipocytes, adipose stromal cells, and immune cells  within  the  microenvironment  of  the  normal  breast,  as  well  as  determining  how  obesity  increases the incidence of breast tumors and promotes the formation of metastasis.


Cancer Biology Graduate Program, Cellular & Molecular Pathology (CMP), Comparative Biomedical Sciences (CBMS), Endocrinology and Reproductive Physiology (ERP), Molecular and Cellular Pharmacology (MCP), Molecular and Environmental Toxicology (METC)

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