Lisa Arendt
Credentials: Comparative Biosciences Department
Position title: Obesity, breast cancer, mouse models
Email: lmarendt@wisc.edu
Phone: (608) 890-2265
Address:
Veterinary Medicine Building
2015 Linden Dr
Madison, WI 53706
LAB WEBSITE:
FOCUS GROUPS:
Cancer Biology; Immunology
RESEARCH DESCRIPTION:
Obesity is becoming a global epidemic in both adults and children, leading to increased rates of multiple types of cancer including breast, kidney, colorectal, pancreatic, and esophageal. Elucidating the role of adipose tissue biology in cancer is critical for prevention and treatment of obesity-‐associated cancer. My research goal is to examine the interactions among the epithelia and stromal cells that are deregulated under conditions of obesity leading to tumorigenesis, and our work is currently focused on breast cancer. We are interested in understanding how obesity alters cell signaling among stromal cells, including adipocytes, adipose stromal cells, and immune cells within the microenvironment of the normal breast, as well as determining how obesity increases the incidence of breast tumors and promotes the formation of metastasis.
ALSO A TRAINER IN THE FOLLOWING PROGRAMS:
Cancer Biology Graduate Program, Cellular & Molecular Pathology (CMP), Comparative Biomedical Sciences (CBMS), Endocrinology and Reproductive Physiology (ERP), Molecular and Cellular Pharmacology (MCP), Molecular and Environmental Toxicology (METC)