Position title: Pluripotent Stem Cell Immunogenicity
600 Highland Avenue
Madison, WI 53706
Cell Adhesion & Cytoskeleton; Developmental Biology & Regenerative Medicine; Immunology
The Brown Lab focuses on exploring the nexus of pluripotent stem cell (PSC) biology and immunology. We are currently investigating the mechanisms underpinning the immune response to autologous and allogeneic PSC-derived cardiovascular cell therapies. Using transplantation immunology and genomics-based strategies, in conjunction with humanized and primatized mouse models, our goals are to 1) improve traditional solid organ transplantation outcomes, 2) gain new insights into PSC biology and immunology, and 3) enable curative regenerative medicine therapies.