Matthew E. Brown

Credentials: Surgery

Position title: Pluripotent Stem Cell Immunogenicity

Email: brownm@surgery.wisc.edu

Phone: 608-263-1727

Address:
H4/733 CSC
600 Highland Avenue
Madison, WI 53706

LAB WEBSITE:

https://www.surgery.wisc.edu/research/researchers-labs/brown/

FOCUS GROUPS:

Cell Adhesion & Cytoskeleton; Developmental Biology & Regenerative Medicine; Immunology

RESEARCH DESCRIPTION:

The Brown Lab focuses on exploring the nexus of pluripotent stem cell (PSC) biology and immunology. We are currently investigating the mechanisms underpinning the immune response to autologous and allogeneic PSC-derived cardiovascular cell therapies. Using transplantation immunology and genomics-based strategies, in conjunction with humanized and primatized mouse models, our goals are to 1) improve traditional solid organ transplantation outcomes, 2) gain new insights into PSC biology and immunology, and 3) enable curative regenerative medicine therapies.

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