Credentials: Anesthesiology Department
Position title: Molecular mechanisms of pain
1111 Highland Ave
Madison, WI 53705
Limited and ineffective treatments options for high intensity chronic pain result in tremendous and pervasive suffering. My group is interested in the signaling mechanisms that govern pain-associated behavior. Despite widespread recognition that long lived changes in the activity of neurons that amplify painful cues hinge on de novo protein synthesis, the targets of induced translation and mechanisms that govern protein synthesis in sensory neurons are poorly understood. We focus on mRNA and all of the key steps that link events that occur on the membrane to ribosomes.