Silvia Cavagnero

Credentials: Chemistry Department

Position title: Protein folding and aggregation in the cell, molecular chaperones, role of the ribosome in protein folding


Phone: (608) 262-5430

5351a F Daniels & Jh Mathews Chem Bl
1101 University Ave
Madison, WI 53706


lab website:

focus groups:

Molecular & Genome Biology of Microbes; RNA Biology; Systems Biology

research description:

Our lab focuses on exploring the principles that govern protein folding and misfolding in the cellular environment. The group specifically addresses kinetic and structural aspects and employs a variety of methods including in vitro transcription-translation, incorporation of unnatural amino acids into proteins, fluorescence spectroscopy and microscopy, nuclear magnetic resonance, mass spectrometry, ultrarapid mixing, and cell-free transcription/translation. We are particularly interested in unveiling the general rules underlying the in vivo folding and misfolding of small cytoplasmic proteins at the amino-acid-specific level.

ALSO A TRAINER IN THE FOLLOWING PROGRAMS: ChemistryIntegrated Program in Biochemistry (IPiB), Microbiology Doctoral Training Program (MDTP), Biophysics, Quantitative Biology Initiative (QBI)

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