Josh Coon
Credentials: Biomolecular Chemistry
Position title: Systems and quantitative biology
Email: jcoon@chem.wisc.edu
Phone: 608-263-1718
Address:
4266 Biochemical Sciences
440 Henry Mall
Madison, WI 53706
LAB WEBSITE:
FOCUS GROUPS:
Cellular & Molecular Metabolism, Developmental Biology & Regenerative Medicine, Systems Biology
RESEARCH DESCRIPTION:
My laboratory innovates mass spectrometry (MS) technology to accelerate the pace, depth, and accuracy of proteome analysis and applies these technologies to globally access proteome structure, function, and regulation. Having established our reputation in proteomics instrumentation, our mission now includes leveraging mass spectrometry for measurement of nucleic acids, metabolites, and lipids. With novel multi-omics technology, we aim to deliver an integrated platform for rapid and comprehensive analysis of the biological state. The rationale is simple: fully understanding a biological system requires knowing the interplay between molecular classes. Finally, the newest domain of our research portfolio aims to innovate technologies for high-throughput measurement of protein structure. By bridging MS and electron microscopy (EM), with concepts from astrophysics, we have developed a new strategy to overcome pervasive limitations in sample vitrification.
ALSO A TRAINER IN THE FOLLOWING PROGRAMS:
Chemistry, Integrated Program in Biochemistry (IpiB), Biophysics, Biotechnology Training Program (BTP), Genomic Sciences Training Program (GSTP), Computation and Informatics in Biology & Medicine (CIBM)