Credentials: Nutritional Sciences Department
Position title: Mammalian cellular metabolism; metabolic regulation; tumor microenvironment
1415 Linden Dr
Madison, WI 53706
Cellular & Molecular Metabolism; Systems Biology
The overarching goal of my research is to understand how mammalian cellular metabolism is reprogrammed in response to changes in the environment and cellular state, and how activities in key metabolic pathways can in turn affect cell function. To study this, we combine systems biology approaches, especially fluxomics and metabolomics, with computational modeling and biochemical and genetic techniques. Particularly, our current works focus on (1) understanding the metabolic adaptations in cancer cells in acidic tumor microenvironment, and (2) investigating the metabolic regulation during macrophage polarization.