Integrative Biology Department
Morphogenesis and pattern formation during early development
327 Noland Zoology Building
250 N Mills St
Madison, WI 53706
Developmental Biology & Regenerative Medicine; Cell Adhesion & Cytoskeleton
Our laboratory studies the cellular and molecular mechanisms of cell adhesion and cell movements during embryonic development, using C. elegans as a model organism. We are interested in (1) the cellular and molecular mechanisms of cell rearrangement; (2) the cellular and molecular mechanisms of epithelial sheet sealing; and (3) the cellular and molecular mechanisms underlying cadherin-based adhesion during morphogenesis. We use genetics, high resolution 4d imaging of tagged proteins in living embryos, biochemistry, and embryology to study these processes.