Jeffrey Hardin

Integrative Biology Department

Morphogenesis and pattern formation during early development

jdhardin@wisc.edu

(608) 262-9634

327 Noland Zoology Building
250 N Mills St
Madison, WI 53706

Headshot

lab website:

http://worms.zoology.wisc.edu/

focus groups:

Developmental Biology & Regenerative Medicine; Cell Adhesion & Cytoskeleton

research description:

Our laboratory studies the cellular and molecular mechanisms of cell adhesion and cell movements during embryonic development, using C. elegans as a model organism. We are interested in (1) the cellular and molecular mechanisms of cell rearrangement; (2) the cellular and molecular mechanisms of epithelial sheet sealing; and (3) the cellular and molecular mechanisms underlying cadherin-based adhesion during morphogenesis. We use genetics, high resolution 4d imaging of tagged proteins in living embryos, biochemistry, and embryology to study these processes.

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