Credentials: Biomolecular Chemistry
Position title: High-Throughput Mammalian Functional Genomics
West Wedge 2768
1111 Highland Ave.
Madison, WI 53706
Cancer Biology; Systems Biology; Transcriptional Mechanisms
We use high-throughput screening platforms and next-generation sequencing to perform functional genomics in mammalian cells. We use these technologies to explore how genotypes are related to human health, including disease state and treatment response. These tools are broadly applicable, but our lab uses them to explore mammalian DNA repair and transcriptional regulation, common targets for therapeutic intervention in cancer. In addition to identifying new machinery, we investigate how host and pathogenic factors perturb these processes and alter the response to therapeutic strategies.