Credentials: Comparative Biosciences Department
Position title: Mechanotransduction and the regulation of skeletal muscle mass
Phone: (608) 890-2174
4256 Veterinary Medicine Building
2015 Linden Dr
Madison, WI 53706
Cell Adhesion & Cytoskeleton; Cellular & Molecular Metabolism; Cancer Biology
It is well recognized that mechanical stimuli play a major role in the regulation of skeletal muscle mass, and that the maintenance of muscle mass contributes significantly to disease prevention and the quality of life. Although the link between mechanical signals and the regulation of muscle mass has been recognized for decades, the molecular mechanisms that drive this process remain poorly defined. Hence, the long-term goal of our research is to determine how skeletal muscles sense mechanical information and convert this stimulus into the molecular events that regulates changes in muscle mass (i.e., mechanotransduction).