Anna Huttenlocher
Credentials: Pediatrics Department
Position title: Cell migration; inflammation; innate immunity
Email: huttenlocher@wisc.edu
Phone: (608) 265-4669
Address:
4205 Microbial Sciences Building
1550 Linden Dr
Madison, WI 53706
LAB WEBSITE:
https://huttenlocher.labs.wisc.edu/
FOCUS GROUPS:
Cell Adhesion & Cytoskeleton; Immunology
RESEARCH DESCRIPTION:
Our research is at the interface of cell biology and immunology and is centered on understanding on inflammation and its resolution during tissue repair. We seek to dissect how external cues and cell signaling networks regulate cell migration and how this is altered in human disease. Our group has pioneered approaches to visualize and manipulate leukocyte motility in zebrafish and human cells, and using these tools have uncovered new mechanisms that regulate resolution of innate immune inflammation. We are also engineering human pluripotent stem cells to understand neutrophil migration and host defense responses that are studied in microfluidic and organotypic models. We are also engineering human pluripotent stem cells to understand neutrophil migration and host defense responses that are studied in microfluidic and organotypic models.