Comparative Biosciences Department
Transcriptional control of gonad development
4354c Veterinary Medicine Building
2015 Linden Dr
Madison, WI 53706
Developmental Biology & Regenerative Medicine; Physiology; Transcriptional Mechanisms
We use genetic and molecular approaches to understand developmental processes required for fetal gonadogenesis. Specific investigations focus on cell-cell interactions that promote follicle formation and oocyte survival and the onset and maintenance of steroidogenesis in developing female and male gonads respectively. New knowledge gained from developmental studies is extended to sex specific adult diseases, in particular, premature ovarian failure in females and the onset of steroidogenesis in aggressive castration resistant prostate cancer in males.