Credentials: Medical Microbiology & Immunology Department
Position title: Aspergillus cell biology
Phone: (608) 262-9795
3476 Microbial Sciences Building
1550 Linden Dr
Madison, WI 53706
Molecular & Genome Biology of Microbes; Cellular & Molecular Metabolism
Our laboratory works on identifying cellular and genetic regulation of secondary metabolite gene clusters in Aspergillus spp. These clusters may be important in virulence such as with the plant pathogen A. flavus or human pathogen A. fumigatus. We identify when the metabolites are produced, where in the fungal thallus they are produced and their impact on host and/or possible use as drug therapies. We are also interested in identifying new metabolites for antibiotic use and develop novel molecular techniques to heterologously express fungal natural products in host fungi.