Jessica Lang

Credentials: Pathology & Laboratory Medicine

Position title: Translational ovarian cancer epigenetics

Email: kueck@wisc.edu

Phone: (608) 262-8601

Address:
WIMR 2766
1111 Highland Ave
Madison, WI 53705

LAB WEBSITE:

jessicalanglab.pathology.wisc.edu / pathology.wisc.edu

FOCUS GROUPS:

Cancer Biology; Transcriptional Mechanisms

RESEARCH DESCRIPTION:

My scientific mission is to leverage genomics and epigenetics in ovarian cancer (OvCa) models to produce translational and impactful science building on my research in somatic mutations in chromatin remodeling factors and epigenetic dysfunction through the following research goals: 1) Understand dynamics of epigenetic features following chemotherapy treatment and resistance; 2) Identify potential therapies for treatment that exploit epigenomic features; 3) Integrate epigenomic features with somatic cancer mutations towards a more comprehensive OvCa picture. I will approach these research goals using human cell lines and tumor tissue to identify shared and necessary OvCa enhancers, validated by innovative functional epigenomics approaches and preclinical models. I will also continue my history of scientific collaborations and clinical partnerships to support my research and ensure clinical translation of findings.

PERFORM A PUBMED PUBLICATION SEARCH