Ci Ji Lim

Credentials: Biochemistry Department

Position title: Human telomere maintenance and genome maintenance

Email: ciji.lim@wisc.edu

Phone: 608-265-4690

Address:
315c Biochemistry Labs
433 Babcock Dr.
Madison, WI 53706

LAB WEBSITE:

https://biochem.wisc.edu/people/lim/

FOCUS GROUPS:

Cancer Biology

RESEARCH DESCRIPTION:

Telomeres are repetitive DNA and associated proteins at the ends of linear chromosomes. They protect our chromosome ends from being misread as broken ends, underlining the importance of telomeres for genome stability, and they also serve as a “clock” for our biological lifespan. Our lab seeks to investigate the molecular mechanisms of human telomere maintenance using an interdisciplinary approach. This includes structural studies using cryo-electron microscopy (cryo-EM) and spatial/temporal studies at the chromatin level using single-molecule techniques. Specially, our lab focuses on two major areas – 1) Telomere chromatin organization and 2) Telomere replication mechanism.

ALSO A TRAINER IN THE FOLLOWING PROGRAMS:

Integrated Program in Biochemistry (IpiB), Biophysics, Biotechnology Training Program (BTP), Genetics

PERFORM A PUBMED PUBLICATION SEARCH