Valentina Lo Sardo
Credentials: Cell and Regenerative Biology Department
Position title: Human genetic variations in cardiovascular and cancer biology
Email: losardo@wisc.edu
Phone: 608-265-5624
Address:
1111 Highland Ave
Madison, WI 53705
LAB WEBSITE:
FOCUS GROUPS:
Cell Adhesion & Cytoskeleton; Physiology; Transcriptional Mechanisms
RESEARCH DESCRIPTION:
Research in my lab combines pluripotent stem cell potential and functional genomics to understand how common genetic variants among individuals, including those in non-coding portions of the genome, contribute to altering cell physiology, cell state, and fate commitment. Emphasis is posed on understanding non-coding risk factors, cell-type vulnerability, and ethnicity-based susceptibility to human diseases. Using multidisciplinary approaches, including pluripotent stem cell (PSC) differentiation, genome editing, transcriptomics, imaging, and proteomics, my lab aims to identify new molecular mechanisms triggering cardiovascular disease and cancer.