Credentials: Comparative Biosciences Department
Position title: Replication-coupled DNA repair
Veterinary Medicine Building
2015 Linden Dr.
Madison, WI 53706
Cancer Biology, Virology
The replication stress response is required to repair DNA lesions that arise due to both endogenous sources and environmental genotoxins found in water, food, and industrial chemicals. This proposal aims to discover how DNA-strand specific obstacles contribute to mutagenesis, the differential replication stress response associated with strand-specific obstacles, and how genotoxins influence strand-based mutagenesis. My lab aims to characterize how cells prevent mutagenesis in a new context uncovering mechanisms in DNA repair.