Radiotherapy to immune-modulate tumor microenvironments
3131 Wi Institute Medical Research
1111 Highland Ave
Madison, WI 53705
Cancer Biology; Immunology
The efforts of my translational research laboratory focus on examining the mechanisms and pre- clinical testing of treatment strategies that combine radiation and molecular-targeted therapeutics to drive anti-tumor immune responses. Our experimental approach is founded on robust in vivostudies in murine tumor models and is augmented by ex vivo and in vitro approaches that include immuno-histopathology, cellular immune function assays, radio-sensitivity assays, flow cytometry, as well as molecular and cellular biology techniques.