Claire O'Leary

LAB WEBSITE:

O’Leary Lab

FOCUS GROUPS:

Developmental Biology & Regenerative Medicine, Immunology, Physiology

RESEARCH DESCRIPTION:

Dr. O’Leary began her training as an immunologist studying how protein degradation regulates T cell activation
and cytokine responses, using in vitro, in vivo and proteomic techniques. She completed her postdoctoral work
at UCSF, working on the role of tuft cells in regulating small intestinal and biliary immunity. Dr. O’Leary is
starting her lab in the Department of Pediatrics, and is excited to continue working on tuft cells, microbiomehost
interactions, and the gastrointestinal tract using in vivo mouse models, ex vivo tissue analysis, and
sequencing approaches to uncover new mechanisms regulating inflammation at mucosal sites.

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