Marina Sharifi
Credentials: Department of Medicine
Position title: Targeted therapy resistance in advanced cancer
Email: msharifi@medicine.wisc.edu
Phone: 608-263-3618
Address:
Clinical Science Center
600 Highland Ave
Madison, WI 53792
LAB WEBSITE:
FOCUS GROUPS:
Cancer Biology
RESEARCH DESCRIPTION:
The Sharifi lab is focused on identifying molecular mechanisms of targeted therapy resistance in advanced breast and prostate cancer to develop new and more effective therapies. Our research utilizes translational liquid biopsy based approaches and patient derived models to evaluate dynamic changes in endocrine and oncogene signaling that occur in response to estrogen, androgen and PI3K pathway targeted therapies in patients with hormone dependent cancers. The overarching goal of our work is to develop new strategies to overcome targeted therapy resistance through a better understanding of the molecular changes that drive resistance in patients.
ALSO A TRAINER IN THE FOLLOWING PROGRAMS:
Physician Scientist Training Program