Position title: Genomics of brain development and disorders
Phone: (608) 262-3113
425 Henry Mall, Room 5262
Madison, WI 53706
Developmental Biology & Protein Trafficking; RNA Biology; Systems Biology
The Werling Lab is interested in investigating the key neurobiological mechanisms involved in the etiology of autism spectrum disorder (ASD) and other neuropsychiatric disorders, including the dimensions of genetic variation, development, and sex-differential biology, and interactions between them. We apply genome-wide genetics, functional genomics, and bioinformatics approaches (e.g. RNA-seq, single cell analyses, eQTLs) in human tissue and model systems to identify and characterize the mechanisms involved in sex-differential and disorder-associated neurobiology. The long-term goal of our research program is to uncover fundamental causal pathways in both sexes that will facilitate treatment development and benefit affected individuals and their families.