Jingshing Wu
Credentials: Pediatrics Department
Position title: Developmental Biology, Congenital Heart Disease, Genetics/Epigenetics
Email: jwu7@wisc.edu
Address:
Wi Institute Medical Research
1111 Highland Ave
Madison, WI 53705
LAB WEBSITE:
FOCUS GROUPS:
Cellular and Molecular Metabolism, Developmental Biology & Regenerative Medicine, Transcriptional Mechanisms
RESEARCH DESCRIPTION:
Cardiac development is precisely regulated by the interplay of several transcription factors within a network. How these transcription factors mechanistically interact and how perturbation of the transcription factor network results in congenital heart disease requires further elucidation. Through the use of advanced microscopy, single cell sequencing technologies, proteomics, and functional assays, we have identified key players and pathways of the transcription factor network regulating cardiac development and how various insults can disrupt these elements leading to congenital heart disease. Results from this work will not only further our understanding of cardiac development, but will also identify therapeutic candidates.
ALSO A TRAINER IN THE FOLLOWING PROGRAMS:
Molecular and Cellular Pharmacology Training Program (MCP)