Credentials: Genetics Department
Position title: Cellular/molecular mechanisms of memory formation and psychiatric dysfunction
Phone: (608) 262-5014
3434 Genetics-Biotech Center Bldg
425 Henry Mall
Madison, WI 53706
Transcriptional Mechanisms; RNA Biology; Systems Biology
We use molecular, genetic and cellular approaches to answer questions on neuronal function and dysfunction. We are focused on how memories are formed and persist in the brain. Circadian and sleep-related processes are part of this process. Most of our work centers around the cAMP/PKA/CREB signaling pathway. In fly models of disease, sleep and cAMP signaling are prodromal endophenotypes that are causally involved in disease progression. We are interested in why they are dysfunctional, and how to overcome their problems.