Hematopoietic stem cell, leukemic stem cell, cytokine signaling
7453 Wi Institute Medical Research
1111 Highland Ave
Madison, WI 53705
Cancer Biology; Developmental Biology & Regenerative Medicine
My lab focuses on identification of novel genetic driver mutations in promoting chronic leukemia formation and its malignant transformation to an acute phase using whole exome sequencing. These candidate mutations will subsequently be cloned and validated in leukemia cell lines in vitro and genetically engineered mouse models in vivo.