Timothy Kamp
Credentials: Medicine Department
Position title: Mechanisms of arrhythmias and cardiac regeneration
Email: tjk@medicine.wisc.edu
Phone: (608) 263-1172
Address:
8459 Wi Institute Medical Research
1111 Highland Ave
Madison, WI 53705
LAB WEBSITE:
FOCUS GROUPS:
Developmental Biology & Regenerative Medicine; Membrane Biology & Protein Trafficking; Physiology
RESEARCH DESCRIPTION:
Human pluripotent stem cells are a central element of the research. These master stem cells can differentiate into all the major cell types present in the heart, providing unlimited quantities of human heart cells for research and therapeutic applications. The Kamp lab has pioneered this
technology, developing ever-improving methods for the robust production of cardiomyocytes from human pluripotent stem cells and other cell populations such as cardiac fibroblasts. Ongoing research examines the genetic basis of inherited arrhythmias and cardiomyopathies using patient-specific induced pluripotent stem cells and cellular electrophysiology. Research focuses on defining the impact of genetic variants that cause abnormal rhythms and heart
function at the cellular level to identify targets and pathways for therapy. The lab is also actively pursuing strategies to re-muscularize the failing heart following myocardial infarction. Using a variety of small and large animal models in collaborative studies, we are developing and testing different cell preparations derived from human pluripotent stem cells and delivery strategies.
ALSO A TRAINER IN THE FOLLOWING PROGRAMS: Medical Scientist Training Program (MSTP), Molecular and Cellular Pharmacology (MCP), Cellular and Molecular Pathology (CMP), Comparative Biomedical Sciences Graduate Program